i got a similar bug as Done25 has, i had already beaten the boss, but the game just continued as nothing happened, so i kept playing, at some poing, i was having a huge invasion from the left side that i totally didn't expect (so far i only had really small invasions, before i tried to explore a bit deeper there), so when i was going to train my troops the selection just froze in a building, and i couldnt train more troops neither unselect or select something else, i dont know what would happen if i was destroyed because i closed the window before they could defeat me as by base was so extense, so i dont know if you cant also loose, because killing the boss wont do anything)
PS: i played in hard mode only